This article analyzes the work done by the Swedish prisoner of the Great Northern War Philip Johan Tabbert von Strahlenberg during his stay in Siberia and aimed at exploring ancient and traditional cultures of Western Siberia and the Minusinsk Basin. A brief overview of earlier studies is presented. The conditions of Strahlenberg’s work are outlined. His main interests, from his arrival in Siberia’s capital until his return to Sweden, concerned the cartography, ethnology, and archaeology of the environs of Tobolsk and of the entire Western Siberia, Minusinsk Basin, and Southern Siberian highlands in particular. Some episodes in Strahlenberg’s activities as a researcher and collector are described with a focus on the difficulties he experienced, specifically when collecting ancient artifacts and written documents. Certain results of his research are highlighted. From the modern standpoint, the article examines the significance of Strahlenberg’s work for Russian archaeology at the stage when its basis of sources was being formed. His place among the first experts in Western and Southern Siberian ancient and traditional cultures is assessed. The key role in the organization and consolidation of research in the remote fringes of the Russian State in the early 1700s belonged to the Russian Academy of Sciences.